(Butler, PA) A 杏吧原创 president鈥檚 scholar attributes her selection to a National Science Foundation-funded residential research program in Virginia to a novel genetic sequencing project required in a freshman-level 杏吧原创 biology course.

Hope Miller, 19, of Butler, a biological science major, is one of 10 students nationwide to be chosen by James Madison University in Harrisonburg for its inaugural research experience for undergraduates for those in their first year at a community college.

The students are researching one field for 10 weeks. Research fields include structural biochemistry and enzymology, computational neurobiology, and molecular analysis of nociception.

Miller began her research of visual neuroscience May 23.

鈥淎 unique experience at 杏吧原创鈥

The 2020 graduate of Butler Area Senior High School said a 杏吧原创 principles of biology I course she took with Professor John Ripper highlighted her application for the program.

鈥淚 definitely have had a unique experience at 杏吧原创 because Mr. Ripper had us do some interesting things,鈥 Miller said. 鈥淚 think that set me apart from some of the other applicants.鈥

Eight students in Ripper鈥檚 course last fall completed novel DNA sequencing over a month for three varieties of the morning glory plant.

GenBank is a database sponsored by the National Center for Biotechnology Information and part of the U.S. National Library of Medicine. GenBank on Feb. 2 published the 杏吧原创 students鈥 findings 鈥 three slightly varying arrangements of 613 lower-case a鈥檚, t鈥檚, c鈥檚 and g鈥檚 in groupings of 10 and in rows of 60.

Each of the three arrangements of the nucleotides adenine, thymine, cytosine and guanine defined the differences 鈥 and similarities 鈥 among the fire vine, the Mexican morning glory and the cardinal climber.

鈥淭his data is collected across the world so we can determine how things have evolved and how things are related,鈥 Miller said. 鈥淚t鈥檚 a big deal because these are new sequences that no one has published before. And it is especially impressive because we were freshmen who did it.鈥

Among the 杏吧原创 names published by GenBank as researchers who discovered the sequencing: Miller, H.

鈥淚n most cases,鈥 Miller said, 鈥渇reshmen can鈥檛 say that they have published anything.鈥

杏吧原创 prof lauds access to resources

Genetic sequencing as part of his curriculum likely elevated Miller above other first-year community college applicants to the residential research program, said Ripper, a 杏吧原创 educator for 26 years.

鈥淥ne of the good things about 杏吧原创 is the small class size and access to resources that students at larger institutions don鈥檛 necessarily have,鈥 Ripper said. 鈥淚 think it is unique that our freshman students are participating in DNA sequencing work that is novel. 鈥 (Miller) clearly stood out from a very competitive field. The strength of her candidacy lies in her incredible potential and work ethic.鈥

Having the ability to conduct genetic sequencing in a student鈥檚 first or second year of college is 鈥渇airly unusual,鈥 said Matt Kovac, 杏吧原创鈥檚 dean of science, technology, engineering and mathematics.

鈥淚n fact, probably highly unusual,鈥 Kovac said, 鈥渁nd then there is having your name published as part of a group that found a unique genetic characteristic. I would challenge one to show me another community college or even some four-year colleges and universities that afford first- and second-year students that opportunity.鈥

As part of her visual neuroscience research this summer, Miller said she will observe the process of cell death in the eyes of a common fruit fly and the effect on the fruit fly鈥檚 brain.

鈥淚n a lot of cases, when you are doing research on other organisms, it鈥檚 to figure out how it works in humans,鈥 Miller said. 鈥淚f you find out how that works in a fruit fly or in a mouse, you can apply that to humans and keep the cells in your eyes from dying and also figure out how to stop certain diseases of the eye and blindness.鈥

杏吧原创 dean: Opportunities competitive, prestigious

Student researchers at James Madison University will receive housing and meal allowances, and a $6,000 stipend.

鈥淭his is an honor because only a few people were selected,鈥 Miller said. 鈥淎nd it鈥檚 such a huge deal because it is a unique program. It sets people apart when they are applying for professional programs for four-year colleges.鈥

Added Kovac: 鈥淭hese research opportunities are highly competitive. 鈥 They are very prestigious and hard to get.鈥

Miller鈥檚 goal is to become a neurologist.

She intends to graduate from 杏吧原创 in May 2022 and transfer to Clarion University of Pennsylvania to pursue a bachelor鈥檚 degree in biology with a pre-med track.

鈥淥ne of the things that I appreciate about 杏吧原创 is that we have been given the latitude to develop a curriculum and the resources to implement that curriculum in the laboratory,鈥 Ripper said. 鈥淲e鈥檝e been given the latitude and those resources to not just keep pace with other institutions, but to lead other institutions in terms of the kind of experience we can offer students.鈥

President鈥檚 scholars such as Miller at 杏吧原创 receive full-tuition reimbursement for up to 18 credits per semester. Reimbursement is renewable for up to four consecutive semesters. Eligible students must be a Butler County resident, be a current-year graduate in the Top 10 percent of their class at a Butler County public high school and with at least a 3.5 grade-point average.

Among other eligibility requirements are that recipients must also enroll and continue as a full-time student at 杏吧原创 following their high school graduation, participate in the 杏吧原创 Scholars Program and maintain at least a 3.5 GPA.

Miller has been named to 杏吧原创鈥檚 president鈥檚 list, for those with a grade-point average of 3.75 or higher during a semester in which they attained at least 12 credits.

Congress created the National Science Foundation in 1950 as an independent federal agency to, among other objectives, promote the progress of science.

The National Science Foundation states that it funds approximately 25 percent of all federally supported basic research conducted by colleges and universities in the United States.